Cold storage of human precision-cut lung slices in TiProtec preserves cellular composition and transcriptional responses and enables on-demand mechanistic studies

Abstract Background Human precision-cut lung slices (hPCLS) are a unique platform for functional, mechanistic, and drug discovery studies in the field of respiratory research.However, tissue availability, generation, and cultivation time represent important challenges for their usage.Therefore, the present study evaluated the efficacy of a specific

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